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Melior Discovery urogenital Micturition : Diet-Induced Stress and Overactive Bladder After a 24-hour fast, mice were injected with vehicle and 1.0 mL water subcutaneously. Oxybutynin (100mg/kg) was orally administered 5 minutes after water administration and mice were placed in the automated chambers for 90 minutes. Oxybutynin caused a significant increase in latency for first urination event (A) as well as a reduction in urination volume (B). Data are mean ± SEM; **p<0.01, ***p<0.001 compared to vehicle.
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